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Introduction Ewing sarcomas primitive neuroectodermal tumors
2019-08-08
Introduction Ewing sarcomas/primitive neuroectodermal tumors (ES/PNETs) are relatively infrequent but the second most common sarcoma of the bone next to osteosarcoma. Nearly 80% of them occur in persons younger than 20years. Most of them arise from the bone, but 10 to 20% of them from soft tissue.
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Herein we further established a dynamic DNA
2019-08-08
Herein, we further established a dynamic DNA self-assembly activated hemin-mimetic enzymes system by embedding DNA-hemin into an entropy-driven DNA-assembly for fluorescent biosensing. The entropy-driven dynamic DNA-assembly is one of the toehold-mediated isothermal strand displacement reactions, wh
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In principle in vitro techniques for assessing
2019-08-07
In principle, in vitro techniques for assessing enzyme induction might include the use of cultured hepatocytes, precision-cut liver slices, immortalized Toosendanin lines (such as those derived from hepatomas) and reporter gene constructs
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Dgat−/− mice however had less adipose
2019-08-06
Dgat−/− mice, however, had less adipose tissue, as reflected by lower total fat pad weights and body triglyceride content.
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In addition to PGC1α
2019-08-05
In addition to PGC1α, transcriptional co-repressors such as NCOR and RIP140 participate in oxidative muscle remodeling induced by exercise, whereby reductions in their expression and the resulting de-repression of downstream TFs activates oxidative gene expression (Seth et al., 2007, Yamamoto et al., 2011, Fan et al., 2013).
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Recently, a sandwich-cultured hepatocyte model
2019-08-02
Recently, a sandwich-cultured hepatocyte model has been proved to be a valuable in vitro system that maintains specific hepatic cytomorphology and function relevant to drug metabolism, disposition and toxicity, and thus, closely resembles the in vivo setting.
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CXC chemokines are primarily
2019-08-01
CXC chemokines are primarily expressed in immune organs and the central nervous system: the mouse thymus and spleen (Heesen et al., 1996), chicken bursa (Liang et al., 2001), primate (Macaca mulatta) Teicoplanin A2-2 (Federsppiel et al., 1993) and cattle locus coeruleus, cerebellum and pons (Rimland et al., 1991; Jia and Zhang, 2009).
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The physiological role of the
2019-07-31
The physiological role of the UCNs in the regulation of the HPA axis is still under debate (Fekete and Zorrilla, 2007, Suda et al., 2004).
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Therefore in this study we determined
2019-07-30
Therefore, in this study we determined whether exogenous LTD, a potent agonist of both CysLT and CysLT receptors , induces MLN0128 edema and AQP4 expression in mouse brain; if so, which subtype of the receptors is involved in AQP4 expression in mouse brain and the cultured rat astrocytes.
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Nonaneurysmal subarachnoid hemorrhage
2019-07-29
Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome.
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In all available E2:E3 structures the RING-type
2019-07-27
In all available E2:E3 structures, the RING-type domain binds the E2 on a surface that is remote from the active site Cys (and therefore from the ubiquitin thioester) (Fig. 2).
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As mentioned above there are two
2019-07-26
As mentioned above, there are two major pathways for the DSB repair in mammalian cells, NHEJ and HR/HDR (homology-directed repair) [13], [51].
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In this study the ASTM C1260
2019-07-25
In this study, the ASTM C1260 and ASTM C1567 test methods were followed to conduct the ASR tests. Three mortar bars were prepared using three types of RHA (600-RHA, 150-RHA, and 44-RHA) and CFA.
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Here we examine the associations
2019-07-24
Here, we examine the associations between serum pro and anti-inflammatory cytokines and cognitive functioning in early-stage bipolar I disorder (BDI) patients.
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Acknowledgement This study was supported
2019-07-23
Acknowledgement This study was supported by Vetenskapsrådet, Sweden (Grant 2017-02918). Introduction Soybean is a major source of protein and oil used for food and feed, as well as for the production of industrial products like lubricants and hydraulic fluids (Choudhary and Tran, 2011; Hsien, 2015).
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