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Acknowledgements This work was supported
2019-07-15
Acknowledgements This work was supported by the National Institute of Neurologic Disorders and Stroke (U54 HD061222, 1K23 NS107646-01, and 1K12NS089417-01), Rocky Mountain Rett Association, International Foundation for CDKL5 Research, the Ponzio Family Chair in Neurology Research, and NHMRC Senior Research Fellowship (#1117105).
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The BDNF Val66Met polymorphism
2019-07-13
The BDNF Val66Met polymorphism is also associated with decreased dendritic arborization and impaired long-term potentiation [25]. This is particularly important for the hippocampus, and healthy individuals with a BDNF Val66Met allele have decreased hippocampal volumes [30]. Hippocampal atrophy is common in epilepsy [31] and is observed in individuals exposed to significant prolonged stress [32], which is a model for depression.
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Hello world!
2018-07-29
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