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In addition to PGC1α
2019-08-05
In addition to PGC1α, transcriptional co-repressors such as NCOR and RIP140 participate in oxidative muscle remodeling induced by exercise, whereby reductions in their expression and the resulting de-repression of downstream TFs activates oxidative gene expression (Seth et al., 2007, Yamamoto et al., 2011, Fan et al., 2013).
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Recently, a sandwich-cultured hepatocyte model
2019-08-02
Recently, a sandwich-cultured hepatocyte model has been proved to be a valuable in vitro system that maintains specific hepatic cytomorphology and function relevant to drug metabolism, disposition and toxicity, and thus, closely resembles the in vivo setting.
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CXC chemokines are primarily
2019-08-01
CXC chemokines are primarily expressed in immune organs and the central nervous system: the mouse thymus and spleen (Heesen et al., 1996), chicken bursa (Liang et al., 2001), primate (Macaca mulatta) Teicoplanin A2-2 (Federsppiel et al., 1993) and cattle locus coeruleus, cerebellum and pons (Rimland et al., 1991; Jia and Zhang, 2009).
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The physiological role of the
2019-07-31
The physiological role of the UCNs in the regulation of the HPA axis is still under debate (Fekete and Zorrilla, 2007, Suda et al., 2004).
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Therefore in this study we determined
2019-07-30
Therefore, in this study we determined whether exogenous LTD, a potent agonist of both CysLT and CysLT receptors , induces MLN0128 edema and AQP4 expression in mouse brain; if so, which subtype of the receptors is involved in AQP4 expression in mouse brain and the cultured rat astrocytes.
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Nonaneurysmal subarachnoid hemorrhage
2019-07-29
Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome.
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In all available E2:E3 structures the RING-type
2019-07-27
In all available E2:E3 structures, the RING-type domain binds the E2 on a surface that is remote from the active site Cys (and therefore from the ubiquitin thioester) (Fig. 2).
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As mentioned above there are two
2019-07-26
As mentioned above, there are two major pathways for the DSB repair in mammalian cells, NHEJ and HR/HDR (homology-directed repair) [13], [51].
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In this study the ASTM C1260
2019-07-25
In this study, the ASTM C1260 and ASTM C1567 test methods were followed to conduct the ASR tests. Three mortar bars were prepared using three types of RHA (600-RHA, 150-RHA, and 44-RHA) and CFA.
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Here we examine the associations
2019-07-24
Here, we examine the associations between serum pro and anti-inflammatory cytokines and cognitive functioning in early-stage bipolar I disorder (BDI) patients.
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Acknowledgement This study was supported
2019-07-23
Acknowledgement This study was supported by Vetenskapsrådet, Sweden (Grant 2017-02918). Introduction Soybean is a major source of protein and oil used for food and feed, as well as for the production of industrial products like lubricants and hydraulic fluids (Choudhary and Tran, 2011; Hsien, 2015).
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Many processes can lead to changes
2019-07-22
Many processes can lead to changes in soil P pools over time. Plant-available P (when measured as DGT P) decreased over time for the INORG-P treatment (Fig. 1a).
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Unlike the CRF1 receptor, the CRF2
2019-07-19
Unlike the CRF1 receptor, the CRF2(a) receptor binds and is activated by agonists with a broad range of potencies. Therefore, we assessed the ability of strong and weak ligands to desensitize retinoblastoma CRF2(a) receptors.
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Regardless of its effect on EBV
2019-07-18
Regardless of its effect on EBV infection, the chemokine system has been found to be regulated in both nasopharyngeal cancer and Hodgkin lymphoma. As such, Hodgkin and Reed–Sternberg (HRS) cells from Hodgkin lymphoma and nasopharyngeal carcinoma cells have been shown to express CXCL8 and CCL17.
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Quantum dots (QDs), which exhibit excellent
2019-07-17
Quantum dots (QDs), which exhibit excellent fluorescence quantum yields (QYs), high extinction coefficients and size-tunable narrow emission have highly attracted great interest in various applications such as in solar cells, sensors, and bioimaging [16], [17], [18], [19], [20]. However, QDs suffered from poor chemical/photo-stability toward extreme pH or high ionic strength, which restricts their actual application [21], [22].
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