• br Methods br Results br

  2022-08-11

  

  Methods Results Discussion In the general population BNP has been established as a marker for calculate dilution failure diagnosis. Moreover, there is growing evidence that elevated levels of natriuretic-peptides may improve CV risk prediction in the general population above traditional ri

• br Conclusion The hub gene KIBRA and the

  2022-08-11

  

  Conclusion The hub gene KIBRA and the Hippo signaling pathway were downregulated and miR-21 was upregulated in LAD. MiR-21 promoted the viability and mobility of LAD cells, reduced apoptosis and suppressed the Hippo signaling pathway in LAD through targeting KIBRA. Funding The study was appro

• The Hardy Weinberg equilibrium was

  2022-08-11

  

  The Hardy-Weinberg equilibrium was verified in all groups using the chi-square test. Using WINPEPI 11.65, the number of carriers and non-carriers of the Δ32 allele was compared between the groups through the Pearson's chi-square test with Yates's correction. Two-tailed Fisher's test was used when ap

• GR activity prevents GSSG overaccumulation by reducing this

  2022-08-11

  

  GR activity prevents GSSG overaccumulation by reducing this molecule to GSH (Kranner et al., 2006). High GR activity seems to be essential for undisturbed seed germination as GR and other enzymatic antioxidants maintain sunflower (Helianthus annuus L.) seeds vigour (Bailly et al., 2002). Germination

• Flavopiridol hydrochloride synthesis SGCs tightly ensheath t

  2022-08-11

  

  SGCs tightly ensheath the soma of DRG neurons (Costa and Moreira, 2015, Hanani, 2005, Takeda et al., 2009). Intimate associations between SGCs and neurons facilitate bidirectional regulation of SGC function and neuronal excitability. After nerve injury, neuronal hyperexcitability can result in SGC a

• Naringin has been shown to have significant anti

  2022-08-11

  

  Naringin has been shown to have significant anti-inflammation, anti-oxidative stress, glucolipid metabolic regulation, and myocardial protection effects (Gopinath et al., 2011, Gopinath and Sudhandiran, 2012), suggesting that it may mitigate ADC by inhibiting P2X7 receptors. In the present study, na

• Abnormal expression and higher activity of GLO I

  2022-08-11

  

  Abnormal expression and higher activity of GLO I have been detected more in various tumor MG262 than in normal cell samples., , , , , , , Among cancer cell lines, lung carcinoma cells frequently showed higher GLO1 activity. Human NSCLC cell line NCI-H522 cells possess high activity and expression

• br Conclusion Until recently astrocytes were recognized sole

  2022-08-10

  

  Conclusion Until recently, astrocytes were recognized solely for their maintenance role in the regulation of methylphenol homeostasis. Nowadays, this idea has changed, it is clear that these cells play a crucial role in the regulation of neuronal activity and signal transmission. In particular, g

• AZD0156 receptor br Materials and methods br Results and

  2022-08-10

  

  Materials and methods Results and discussion Conclusions Acknowledgements This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684), and also by t

• A single ICV injection of GALP stimulated food intake

  2022-08-10

  

  A single ICV injection of GALP stimulated food intake in goldfish at 1h post-administration. This result is similar to that observed in rats, where ICV injection of GALP exerted an acute orexigenic effect [14], [15], [16]. Simultaneously, our findings counter the results found in mice, where central

• According to its major function as master regulator of BA

  2022-08-10

  

  According to its major function as master regulator of BA homeostasis, FXR has been shown to have a specific tissue distribution; it is expressed along the entire gastrointestinal tract with a peak in the liver and ileum, as well as in the kidney, and adrenal glands [30], [66], [135]. Low FXR expres

• We have isolated various bioactive peptides acting by bindin

  2022-08-10

  

  We have isolated various bioactive chir99021 acting by binding to the receptors of endogenous bioactive peptides such as opioid, bradykinin, neurotensin, and complements C3a and C5a etc. [24]. Rubimetide is the first example of an agonist peptide of the FPR2 of exogenous origin. Anxiolytic-like ac

• THZ531 br Conclusion In conclusion rats in this

  2022-08-10

  

  Conclusion In conclusion, rats in this model of HELLP syndrome demonstrated increased placental and circulating FasL and increased placental Fas when compared to NP rats. Administration of an ETA receptor antagonist to HELLP rats tended to decrease circulating FasL and placental Fas, while not af

• Our results are consistent with the hypothesis that reduced

  2022-08-10

  

  Our results are consistent with the hypothesis that reduced Fas-mediated apoptosis in maternally activated T-lymphocytes could result in insufficient trophoblast invasion of the spiral Cy5.5 maleimide (non-sulfonated) as the activated T-lymphocytes become able to enhance the destruction of the cyto

• Several named antagonist ligands have figured noticeably in

  2022-08-09

  

  Several named antagonist ligands have figured noticeably in preclinical studies, with proved clear ability to release neurotransmitters and having efficacy in preclinical animal models. Consequently, this has encouraged ongoing research on improved agents with potency, selectivity, and better drug-l

14391 records 359/960 page Previous Next First page 上5页 356357358359360 下5页 Last page